Certified Tissue Bank Specialist (CTBS) Practice Test

Why is it necessary to evaluate for Chagas disease in certain donors?

1. It is transmitted through sexual contact

2. It can result in cardiovascular complications

3. It is a common disease in tropical regions

4. All of the above

The correct answer is: It can result in cardiovascular complications

Evaluating for Chagas disease in certain donors is crucial primarily because the disease can lead to significant cardiovascular complications. Chagas disease, caused by the parasite Trypanosoma cruzi, can remain asymptomatic for years but often progresses to chronic conditions affecting the heart and digestive system. Heart complications can include arrhythmias, cardiomyopathy, and heart failure, which can pose serious risks to recipients of tissue or organ transplants. The other reasons listed, while relevant in a broader context, do not specifically correlate with the critical need for evaluation in donors. For instance, while the transmission of Chagas disease through sexual contact is a concern, it is not the primary method of transmission; it is mostly spread by contact with infected triatomine bugs, blood transfusions, and organ transplants. Furthermore, while Chagas disease is prevalent in certain tropical regions, its geographical distribution does not dictate the necessity for screening in all donor populations. Therefore, the focus on potential cardiovascular complications when assessing donors is paramount to ensure the safety and health of the transplant recipients.